Ear Biomechanics

Implantable Hearing Devices

Ear Tissue Biomechanics

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Orthopaedics

Animal Study

Study on High Intensity Sound

Publications

Peer-Reviewed Journal Papers (Selected from 2017 - present):

 

1.      Jiang, S., Gannon, A., Smith, K., Liang, J., Brown, M. and Gan, R. Z. Prevention of blast-induced auditory injury using 3D printed helmet and hearing protection device 每 A preliminary study on biomechanical modeling and animal. Military Medicine, 2020 (Under Review)

2.      Liang, J., Nakmali, D., Gan, R. Z., Lu, H., and Dai, C. , Investigating the geometry and mechanical properties of human round window membranes using micro-fringe projection. Otology & Neurotology, 2020 (Under Review)

3.      Liang, J., Engles W.G., Smith, K.D., Dai, C., and Gan, R. Z.., Mechanical Properties of Baboon Tympanic Membrane from Young to Adult. J. Association for Research in Otolaryngology (JARO), 2020 (Under Review)

4.      Smith, K., Chen, T., and Gan, R. Z. , Hearing damage induced by blast overpressure at the mild TBI level in a chinchilla model. Military Medicine, Vol. 185: 248-255, 2020

5.      Liang, J., Smith, K., Gan, R. Z., and Lu, H., Effect of blast overpressure on mechanical properties of human tympanic membrane. J. Mech. Behavior Biomed Materials, Vol. 100 (103368): pp. 1-9, 2019.

6.      Gan, R. Z., and Jiang, S. Surface motion change of tympanic membrane damaged by blast waves. J. Biomechanical Engineering, Vol. 141: 091009-1 to -11, 2019

7.      Zhang, T., Gan, R. Z., Gummer, A., and Rosowski,, J. Editorial: MEMRO 2018 每 Middle Ear Mechanics 每 Technology and Otosurgery. Hearing Research, Vol. 378: 1-2, 2019

8.      Luo, H., Wang, F., Cheng, C., Nakmali, D., Dai, C., Wei, L., Gan, R. Z., and Lu, H. Measurement of the through-thickness Young*s modulus of a human tympanic membrane by nanoindentation. Hearing Research, Vol. 378: 75-91, 2019

9.      Chen, T., Smith, K., Jiang, S., Zhang, T., and Gan, R. Z. , Progressive hearing damage after repeated exposure to low level of blast overpressure in chinchillas. Hearing Research, Vol. 378: 33-42, 2019.

10.      Jiang, S., Smith, K., and Gan, R. Z. , Dual-laser measurement and finite element modeling of human tympanic membrane motion under blast exposure. Hearing Research, Vol. 378: 43-52, 2019.

11.      Gan, R. Z., Leckness, K., Smith, K., and Ji, X. D. Characterization of protection mechanisms to blast overpressure for personal hearing protection devices 每 Biomechanical measurement and computational modeling. Military Medicine, Vol. 184, 3/4: 251-260, 2019

12.      Liang, J., Smith, K., Lu, H., Seale, T.W., and Gan, R. Z. Mechanical properties of the Papio anubis tympanic membrane: Change from infancy to adulthood. Hearing Research,,Vol. 370: 143-154, 2018.

13.      Wang, X,. and Gan, R. Z., Surface motion of tympanic membrane in a chinchilla model of acute otitis media. J. Association for Research in Otolaryngology (JARO), Vol. 19: 619-635, 2018.

14.      Jiang S., and Gan, R. Z. Dynamic properties of human incudostapedial joint measured with frequency-temperature superposition. Medical Engineering & Physics, Vol. 54: 14-21, 2018.

15.      Gan, R. Z., Leckness, K., Nakmali, D., and Ji, X. D. Biomechanical measurement and modeling of human eardrum injury in relation to blast wave direction. J. Military Medicine, Vol. 183, 3/4: 245-251, 2018.

16.      Leckness, K., Nakmali, D., and Gan, R. Z. Computational modeling of blast wave transmission through human ear. J. Military Medicine,Vol. 183, 3/4: 262-268, 2018.

17.      Hu, Z., Xu, T., Wang, X., Xie, Z., Luo, H., He, Y., Guo, L., Li, Y., Gan, R. Z., and Lu, H. Fluorescent digital image correlation techniques in experimental mechanics. SCIENCE CHINA Technological Sciences, , Vol. 6(1): 21-36, 2018 (doi: 10.1007/s11431-017-9103-8).

18.      Gan, R. Z., , Jiang, S., and Pineda, M. Age-dependent full-field motion of baboon tympanic membrane. Mechanics of Hearing 2017, Chris Bergevin and Sunil Puria (eds). American Institute of Physics, Melville, NY, pp. 110002-1 to -8, 2018

19.      Liang, J., Yokell, Z., Nakmali, D., Gan, R. Z., and Lu, H. The effect of blast overpressure on the mechanical properties of a chinchilla tympanic membrane. Hearing Research, , Vol. 354: 48-55, 2017. Vol. 354: 48-55, 2017.

20.     Engles, W. G., Wang, X., and Gan, R. Z. Dynamic properties of human tympanic membrane after exposure to blast waves. Annals of Biomedical Engineering , Vol. 45 (10): 2383每2394, 2017.

21.      Guan, X., Seale, T. W., and Gan, R. Z. Factors affecting sound energy transmission in acute otitis media model of chinchilla. Hearing Research, Vol. 350: 22-31, 2017.

22.      Hitt, B., Wang, X., and Gan, R. Z. Dynamic property changes in stapedial annular ligament associated with acute otitis media in the chinchilla. Medical Engineering & Physics, Vol. 40: 65-74, 2017.

  

Conference Papers (Selected from the National and International Conferences: 2017 - 2020

1.      Gan, R. Z., Jiang, S., Smith, K., and Dai, C.  Dual-laser measurement of stapes footplate movement in human ears with and without hearing protection device (HPD) under blast exposure. Association for Research in Otolaryngology (ARO) - Midwinter Meeting , San Jose, CA, January 25-29, 2020.

2.      Jiang, S., Smith, K. Liang, J., Wang, X., Gannon, A., Brown, M., and Gan, R. Z.. A novel chinchilla model of blast-induced auditory injury for hearing damage prediction and prevention using 3D printed ※helmet§ and earplug. Association for Research in Otolaryngology (ARO) - Midwinter Meeting, San Jose, CA, January 25-29, 2020.

3.      Liang, J., Islam, W., Zhang, K., Wang, C., Crooks, S., Gan, R. Z., Tang, Q., Zheng, B., and Dai, C.  A new detection scheme for detection of otitis media with effusion. Association for Research in Otolaryngology (ARO) - Midwinter Meeting , San Jose, CA, January 25-29, 2020.

4.      Liang, J., Luong, V., McCraw, J., Wu, S., Spencer, G., Zhang, K., Myers, R., Gan, R. Z., and Dai, C.   A novel 3D video oculography system for measuring three-dimensional vestibule-ocular reflex. Association for Research in Otolaryngology (ARO) - Midwinter Meeting , San Jose, CA, January 25-29, 2020.

5.      Gan, R. Z., Jiang, S., Smith, K. and Dai, C.  Measurement of middle ear ossicular motion under blast exposure with laser Doppler vibrometry. Proceedings of the Biomedical Engineering Society 2019 Annual Meeting, Philadelphia, PA, October 16-19, 2019.

6.      Brown, M. and Gan, R. Z. Modeling the auditory nerve response during blast exposure Proceedings of the Biomedical Engineering Society 2019 Annual Meeting, Philadelphia, PA, October 16-19, 2019.

7.      Welch, P., Brown, M., Wang, X. and Gan, R. Z.  3D Finite element modeling of blast wave transmission through chinchilla ear. Proceedings of the Biomedical Engineering Society 2019 Annual Meeting, Philadelphia, PA, October 16-19, 2019.

8.      Gan, R. Z., Smith, K., Liang, J., Gannon, A., Brown, M., and Jiang, S.  Prediction and prevention of blast-induced auditory injury using 3D-printed chinchilla ※helmet§ and hearing protection devices. DoD 2018 Military Health System Research Symposium (MHSRS), Kissimmee, FL, August 17-22, 2019.

9.      Gan, R. Z.,Smith, K., Chen, T., and Jiang, S.  Mitigation of auditory damage after blast exposure with glucagon-like peptide-1 (GLP-1) 每 A study in chinchilla. Association for Research in Otolaryngology (ARO) - Midwinter Meeting, Baltimore, MD, February 9-13, 2019.

10.      Brown, M., Ji, X., and Gan, R. Z.   3D finite element modeling of blast wave transmission from the external ear to the cochlea. Association for Research in Otolaryngology (ARO) - Midwinter Meeting, Baltimore, MD, February 9-13, 2019.

11.      Liang, J., Brown, M., Welch, P., Gan, R. Z., Hedjoudje, A., and Dai, C.   Preliminary study of the inner ear mutual mechanics between cochlea and vestibular in finite element simulation. Association for Research in Otolaryngology (ARO) - Midwinter Meeting, Baltimore, MD, February 9-13, 2019.

12.      Welch, P., Smith, K., Brown, M., and Gan, R. Z.   3-D finite element model of the chinchilla ear for modeling sound transmission from ear canal to cochlea. Association for Research in Otolaryngology (ARO) - Midwinter Meeting, Baltimore, MD, February 9-13, 2019.

13.      Gan, R. Z., Chen, T., Smith, K., and Jiang, S.   Therapeutic function of glucagon-like peptide-1 (GLP-1) for hearing restoration after blast exposure. Proceedings of the Biomedical Engineering Society 2018 Annual Meeting, Atlanta, Georgia, October 17-20, 2018.

14.      Brown, M., Jiang, S., and Gan, R. Z.   A 3D printed ear model for standardized testing of hearing protection devices to blast exposure. Proceedings of the Biomedical Engineering Society 2018 Annual Meeting, Atlanta, Georgia, October 17-20, 2018.

15.       Gan, R. Z., Chen, T., Smith, K., Hearing damage induced by blast Overpressure at the mild TBI level in a chinchilla model. DoD 2018 Military Health System Research Symposium (MHSRS), Kissimmee, FL, August 20-23, 2018.

16.       Chandra, N., Shao, N., Rama Rao, K. V., Jiang, S., Chen, T., Brown, M., Gan, R. Z. Central and peripheral auditory abnormalities in animal models of blast-injury. DoD 2018 Military Health System Research Symposium (MHSRS), Kissimmee, FL, August 20-23, 2018

17.       Gan, R. Z., Jiang, S., and Smith, K., Dual-laser measurement and finite element modeling of human tympanic membrane motion under blast exposure. 8 th International Symposium on Middle Ear Mechanics in Research and Otology (MEMRO), Shanghai, China, July 5 每 9, 2018.

18.       Chandra, N., Shao, N., Rama Rao, K. V., Jiang, S., Chen, T., Brown, M., and Gan, R. Z. Central and peripheral auditory injuries in animal models after blast exposure. 8 th International Symposium on Middle Ear Mechanics in Research and Otology (MEMRO),  Shanghai, China, July 5 每 9, 2018.

19.       Chen, T., Smith, K., Jiang, s., Zhang, T., and Gan, R. Z. Progressive Hearing Damage after Repeated Exposure to Low Level of Blast Overpressure in Chinchillas. 8 th International Symposium on Middle Ear Mechanics in Research and Otology (MEMRO),  Shanghai, China, July 5 每 9, 2018.

20.        Luo, H., Wang, F., Chen Cheng, C., Nakmali, D., Dai, C., Li, W., Gan, R. Z. and Lu, H. Measurement of the through-thickness Young*s modulus of a human tympanic membrane by nanoindentation. 8 th International Symposium on Middle Ear Mechanics in Research and Otology (MEMRO),  Shanghai, China, July 5 每 9, 2018.

21.         Gan, R. Z., Chen, T., Smith, K., Jiang, S., Yokell, Z., Tsai Do, B., and Jyung, R., An animal model of cholesteatoma for improvement of middle ear surgical reconstruction. An animal model of cholesteatoma for improvement of middle ear surgical reconstruction., San Diego, CA, February 10-14, 2018.018.

22.         Brown, M., Chen, T., and Gan, R. Z. SEM Imaging of Cochlear Hair Cell Damage Caused by Blast Exposure. Association for Research in Otolaryngology (ARO) - Midwinter Meeting, San Diego, CA, February 10-14, 2018.

23.           Chen, T., Smith, K., and Gan, R. Z. Progressive Hearing Damage after Exposure to Multiple Blasts in Chinchillas. Association for Research in Otolaryngology (ARO) - Midwinter Meeting, San Diego, CA, February 10-14, 2018.

24.           Liang, J. Gan, R. Z., and Lu, H. Measurement of the visco-elastic properties of the chinchilla tympanic membrane. Soc. Exp. Mech., IMAC conference,  Orlando, FL, February 2018.

25.           Gan, R. Z., Chen, T., Smith, K., and Yokell, Z. Hearing damage caused by multiple blast exposure 每 A study on middle ear and cochlea function changes in chinchillas. Proceedings of the Biomedical Engineering Society 2017 Annual Meeting, , Phoenix, Arizona, October 11-14, 2017.

26.           Jiang, S., Smith, K., and Gan, R. Z. Movement of human tympanic membrane under blast exposure measured by laser Doppler vibrometer. Proceedings of the Biomedical Engineering Society 2017 Annual Meeting, , Phoenix, Arizona, October 11-14, 2017.

27.           Brown, M., Ji, X., and Gan, R. Z. 3D Finite element modeling of blast wave transmission from the external ear to the cochlea. Proceedings of the Biomedical Engineering Society 2017 Annual Meeting, , Phoenix, Arizona, October 11-14, 2017.

28.           Gan, R. Z., Leckness, K., Smith, K., and Ji, X. D. Characterization of protection mechanisms to blast overpressure for personal hearing protection devices 每 Biomechanical measurement and computational modeling. DoD 2017 Military Health System Research Symposium (MHSRS), ,Kissimmee, FL, August 27-30, 2017.

29.           Gan, R. Z., Jiang, S., and Pineda, M. Age-dependent full-field motion of baboon tympanic membrane. The 13th International Workshop on the Mechanics of Hearing, Brock University, Ontario, Canada, June 19-24, 2017.

30.           Gan, R. Z., Leckness, K., and Nakmali, D. 3D computational modeling of blast wave transmission through the ear. Association for Research in Otolaryngology (ARO) - Midwinter Meeting, Baltimore, MD, February 11-15, 2017.

31.           Yokell, Z., Nakmali, D., and Gan, R. Z. Switch of MEMR and ABR thresholds after high intensity sound exposure in chinchillas. Association for Research in Otolaryngology (ARO) - Midwinter Meeting, Baltimore, MD, February 11-15, 2017.

32.           Jian S., Wang, X., Nakmali, D., and Gan, R. Z. Measurement of surface motion of human tympanic membrane after blast exposure. Association for Research in Otolaryngology (ARO) - Midwinter Meeting, Baltimore, MD, February 11-15, 2017.

 

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